DIHEXA 10mg

Product Overview

A fundamental standard in neurological and cognitive performance research dictates that exploring advanced neurotrophic agents requires complete structural integrity and verified chemical purity. The Dihexa formulation addresses these demanding benchmarks, serving as a highly purified synthetic peptide derivative developed for precise in vitro and in vivo laboratory modeling. Each vial provides 10mg of pure Dihexa, stabilized as a vacuum freeze-dried (lyophilized) powder maintaining a verified purity profile of greater than 98%.

Dihexa (also known as N-hexanoic-Tyr-Ile-Ahx-NH2) is an oligopeptide drug variant derived from angiotensin IV (AngIV). Characterized by a molecular weight of 532.7 g/mol and a chemical formula of C₂₇H₄₄N₄O₆, this small molecule possesses a distinct structural stability asset over standard endogenous neurotrophins like brain-derived neurotrophic factor (BDNF). Because of its minimized structural framework, Dihexa exhibits exceptional clearance and blood-brain barrier permeability kinetics in laboratory models, allowing it to penetrate cellular microenvironments rapidly and demonstrate high bioactivity without the rapid metabolic breakdown typical of heavy native proteins.

Operating primarily as a potent hepatocyte growth factor (HGF) modulator, Dihexa binds with high affinity to the native HGF ligand. This binding interaction facilitates the dimerization and subsequent activation of c-Met, the receptor tyrosine kinase specific to HGF. Activation of the HGF/c-Met signaling pathway triggers downstream intracellular cascades, notably the mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase/Akt (PI3K/Akt) pathways. Documented research demonstrates that Dihexa actively drives spinogenesis, induces dendritic arborization, and enhances synaptic plasticity. These diverse mechanisms allow for the precise investigation of synaptogenesis biochemistry, neurodegenerative models, and cellular longevity within controlled laboratory settings.

Product Specifications

• Form: Lyophilized (vacuum freeze-dried) powder
• Quantity: 10mg per vial
• Purity: Greater than 98% (verified by HPLC analysis)
• Molecular Weight: 532.7 g/mol
• Primary Target: HGF/c-Met Receptor Complex Agonist
• Primary Research Focus: Synaptogenesis Induction, Spinogenesis Kinetics, and Neuroprotective Pathways

Container Specifications

The physical attributes of the storage vessel directly impact the shelf life of the compound. All research environments should utilize clean, chemically inert containers. Glass vials provide the highest level of protection against gas permeability and chemical interaction, though high-density polypropylene tubes serve as a valid alternative. Keep all stored peptides away from automatic frost-free freezers, as their internal defrost cycles create regular temperature swings that compromise peptide longevity.