MELANOTAN 2 10mg (MT2)

for: Tan; Immune System; Anti-Aging & Sexual Arousal

Melanotan 2 (10mg) is a specialized research peptide utilized primarily to investigate the neuroendocrine regulation of photoprotection, melanogenesis, and sexual function. As a potent non-selective agonist of the melanocortin receptors (MCRs), it is a synthetic analog of the naturally occurring $\alpha$-melanocyte-stimulating hormone ($\alpha$-MSH). Dragon Pharma provides Melanotan 2 10mg at a purity level of 99%+, specifically for use in in-vitro laboratory experiments and preclinical animal models.

Overview

In the realm of dermatological research and metabolic signaling, Melanotan 2 (MT-2) has become a fundamental tool for investigators exploring the systemic regulation of skin pigmentation and energy homeostasis. This compound is a cyclic heptapeptide analog of $\alpha$-MSH that has been engineered for superior stability and receptor affinity compared to its linear predecessors. Dragon Pharma provides Melanotan 2 10mg at a minimum purity of 99%, ensuring that researchers have access to a high-grade Research Peptide capable of producing reproducible and accurate data in complex biological models.

As scientific inquiry into skin cancer prevention, erectile dysfunction, and appetite regulation expands, the need for reliable melanocortin agonists like MT-2 has grown. This expanded profile examines the biochemical characteristics, structural integrity, and multifaceted research applications of Melanotan 2 10mg.

Molecular Characteristics and Chemical Profile

The structural integrity of Melanotan 2 is what allows it to resist rapid enzymatic degradation. By incorporating a lactam bridge to create a cyclic structure, the peptide achieves enhanced potency and a longer biological half-life in research settings.

• Chemical Identity: Melanotan II (MT-II)
• Molecular Formula: C50H69N15O9
• Molecular Weight: 1024.18 g/mol
• Purity: >99% (HPLC and Mass Spectrometry verified)
• Form: Lyophilized powder
• Manufacturer: Dragon Pharma

Research Applications

The peptide is utilized in various scientific investigative domains, including:

• Melanogenesis: Mapping the pathways of melanin production in melanocytes.
• Photoprotection: Investigating the reduction of DNA damage caused by UV radiation.
• Sexual Health: Studying the modulation of erectile function and libido via central nervous system receptors.
• Appetite & Metabolism: Assessing the activation of MC4R in the hypothalamus to control food intake.
• Systemic Inflammation: Studying the immunomodulatory effects of melanocortin signaling.

Pathway and Mechanistic Context

The core value of Melanotan 2 10mg in a laboratory setting is its ability to non-selectively activate MC1, MC3, MC4, and MC5 receptors. In a natural state, $\alpha$-MSH is the primary endogenous ligand; MT-2 bypasses natural limitations by providing a more stable and potent chemical analog.

The Melanocortin Receptor Axis

Upon activation by Melanotan 2, specific physiological shifts occur based on the target receptor:

• MC1R (Skin): Initiates the synthesis of eumelanin (dark pigment), providing a protective barrier against UV-induced oxidative stress.
• MC3R/MC4R (Brain): Facilitates central signaling related to sexual arousal and the suppression of appetite.
• MC5R (Exocrine): Modulates the activity of sebaceous glands and thermoregulation.

Key Mechanistic Shifts:

• Pigmentation Induction: MT-2 promotes the "tanning" response in animal models independently of UV exposure.
• Erectogenic Effects: Activation of central MCRs leads to increased blood flow and arousal signals.
• Energy Balance: By stimulating MC4R, MT-2 promotes a catabolic state, reducing perceived hunger and increasing energy expenditure.

Primary Research Applications

1. Photobiology and Skin Cancer Research

MT-2 is heavily utilized in studies involving the prevention of melanoma. Because it stimulates protective pigmentation without the mutagenic risks of UV radiation, it provides a unique framework for investigating how to shield skin cells from actinic damage.

2. Sexual Dysfunction and Neurotransmission

Known in research circles as a potent inducer of arousal, MT-2 is used to observe how the central nervous system regulates reproductive behaviors. Investigators study changes in neurotransmitter release and the bypass of vascular-only pathways in erectile function models.

3. Obesity and Metabolic Homeostasis

In metabolic research, MT-2 is studied for its "anorexigenic" effects. By activating the hypothalamic melanocortin system, research models examine how MT-2 can influence fat oxidation and reduce food seeking in models of diet-induced obesity.

Source: PubMed

Source: PubMed

Form and Analytical Testing

At Dragon Pharma, the commitment to scientific accuracy begins with a rigorous manufacturing process. Melanotan 2 10mg is produced under strict laboratory conditions to ensure stability and potency.

• Lyophilization for Stability: The compound is supplied in a lyophilized (freeze-dried) form. This process removes moisture while preserving the cyclic peptide structure, ensuring it arrives at your facility in optimal condition.
• Rigorous Analytical Verification: To guarantee a purity level of 99% or higher, every batch undergoes High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm that the chemical signature matches the intended profile.

Product Usage Disclaimer: This product is intended for laboratory and in-vitro research use only. It is not approved for human or veterinary application. Must be handled by qualified professionals. Not for drug, food, or cosmetic purposes. Misuse or misbranding is strictly prohibited.

Author:

All information was searched/edited by Dr. S. Edwin, and Dr. E. Croft who holds a doctorate from Case Western Reserve University School of Medicine