VIP

Product Overview

A core principle in systemic cell signaling research dictates that exploring advanced vasoactive compounds demands both uncompromised structural integrity and verification of chemical purity. The VIP formulation satisfies these rigorous requirements, serving as a highly refined regulatory neuropeptide engineered for precise laboratory investigation into cardiovascular, pulmonary, and immune system dynamics. Each vial delivers pure Vasoactive Intestinal Peptide (VIP), stabilized as a vacuum freeze-dried (lyophilized) powder with a verified purity profile exceeding 98%.

VIP is an endogenous 28-amino acid neuropeptide belonging to the glucagon-secretin superfamily. To optimize its utility in experimental models, its structural sequence is meticulously synthesized to preserve the exact linear architecture required for high-affinity receptor binding. Unlike large, dense proteins that require complex breakdown, its fractional peptide size enables it to pass easily through cellular environments to interface directly with target receptor sites without triggering non-specific immune responses. The compound is defined by its specific primary sequence configuration and optimized for stability in vitro.

Operating as a broad-spectrum regulatory molecule, VIP acts as a potent agonist at specific G-protein coupled receptors, primarily VPAC1 and VPAC2, distributed throughout the central nervous system, smooth muscle tissues, and immune cells. It interfaces directly with these receptors to activate adenylate cyclase pathways, elevating intracellular cyclic adenosine monophosphate (cAMP) levels. Documented research indicates that VIP triggers profound smooth muscle relaxation, induces vascular dilation, and modulates inflammatory cytokine cascades, permitting the detailed investigation of targeted vascular homeostatic mechanisms and neuro-immune interactions in controlled laboratory settings.

Product Specifications

• Form: Lyophilized (vacuum freeze-dried) powder
• Purity: Greater than 98% (verified by HPLC analysis)
• Peptide Class: Vasoactive Intestinal Peptide (28-amino acid sequence)
• Primary Targets: VPAC1 and VPAC2 Receptors
• Target Systems: Cardiovascular, Pulmonary, and Immune Pathways

Container Specifications

The physical attributes of the storage vessel directly impact the shelf life of the compound. All research environments should utilize clean, chemically inert containers. Glass vials provide the highest level of protection against gas permeability and chemical interaction, though high-density polypropylene tubes serve as a valid alternative. Keep all stored peptides away from automatic frost-free freezers, as their internal defrost cycles create regular temperature swings that compromise peptide longevity.